Leaky Gut Gastroparesis

How to Heal Leaky Gut Syndrome

Okay, well, I want to welcome everyone. Thisis Nik Hedberg, and tonight we're talking about how to heal leaky gut syndrome. So,let's get this started. I really enjoy doing these webinars, tryingto get some good information out there to everyone. And leaky gut, it's a big issue.Its main connections are going to be with autoimmune diseases and a variety of chronicconditions, which we'll talk about. I'm just going to cover what it is, what causes leakygut, and then some of the things that you can do about it, and then how we manage itin the practice if it's there. The medical term for leaky gut is gastrointestinalhyperpermeability. It is recognized in conventional

medicine, but it's really not going to berecognized by your average . They kind of look down on it or laugh at it, so to speak,but it is definitely something very real. So, let's go ahead and jump right in. Gettingto the symptoms, conditions associated, conditions connected with leaky gut syndrome, and asI mentioned, autoimmune diseases are a big one, like Hashimoto's thyroiditis, Graves'disease, lupus, Sjögren's, alopecia, rheumatoid arthritis, et cetera. A lot of the symptoms you'll see are fatigue,brain fog. Brain fog is basically inflammation of the brain. Because we don't have pain receptorsin the brain, that's basically how the body

tells us that the brain is inflamed when there'sfogginess. And there's a really strong connection there between the gut and the brain just in general. Weight gain, depression and anxiety. There'sa lot of literature out there connecting chronic inflammation and inflammation in the gut andpsychological issues like depression and anxiety. Different digestive problems, like IrritableBowel Syndrome, Crohn's disease, all sorts of colitis, and then just general symptomslike gas, bloating, cramping, things like that. Food allergies, of course. Arthritis and jointpain, migraine headaches, adrenal gland imbalances,

and then what we call adrenal fatigue, andthen of course asthma and allergies. The gut barrier is called a mucosal barrier,and if there's dysfunction there, there's going to be dysfunction in the other mucosalbarriers like the lungs, for example. So, what is leaky guté What you see here onthe left is what we will call a healthy gut lining. These are what we call villi, they'relike fingers, and that's where all of the absorption occurs in between these gaps. Thisis also where the immune system is. So the gut barrier protects you from a lot of differentthings. It protects you from infections like viruses, bacteria, fungi, parasites, it protectsyou from absorbing undigested protein, and

so it's this mucosal barrier that's very protective. Now, leaky gut is when that barrier becomesbroken down, and you can see it's all flat here, all of the villi have been compromised.And so when you have leaky gut, you can also have malabsorption. That might be kind ofdifficult to understand for some people, but the intestinal barrier is selective, and whenthe immune system becomes compromised, then it can no longer protect you from the varietyof things that we just talked about. Malabsorption means that the absorptive capacityof the gut barrier is not what it used to be, so people will start to develop nutrientdeficiencies and they won't be able to absorb

protein, carbohydrates and fat. So this isa visual of what we call leaky gut. Now, these are some of the main causes. Whatyou see here in the pink is a diagram of the intestinal barrier. I want to give creditto Aristo Vojdani, he is an immunologist for this slide, and Vojdani has spokenextensively on leaky gut. So these are some of the main things thatwe see up here. Dietary proteins and peptides, so that's going to be like gluten, dairy andother allergies; other foods that are highly allergenic; antibodies, and that's if there'ssome kind of infection in the intestine; drugs and xenobiotics, so environmental chemicals,environmental toxins; prescription medications,

Diagnosing Intestinal Motility

What is motilityé Motility in the gut is reallywhat allows us to digest food from the moment we swallow, for it to get processed throughthe stomach, intestine, and eliminated through the colon. When there's a problem anywherealong the way, it can lead to digestive conditions: inability to eat, weight loss, discomfort pain, nausea. It dramatically affects quality of life and can lead to things such as anxiety, depression, social isolation. Because there's not a definitive test, theseindividuals are misdiagnosed, or go years without a diagnosis. What we do iscome up with a diagnosis. We may not have

a cure, but often times, giving them a diagnosis, helps them live with their condition much better. Motility abnormalities are hard to diagnosebecause there's multiple abnormalities that occur. These conditions affect the nervesin the GI tract. The brain controls the gut, but visaversa, conditions that affect thegut can also affect the brain: cognition, emotion. So, you get into this vicious cyclewhere yes, a lot of individuals with motility abnormalities do have anxiety, but it'stheir GI problems that lead to the anxiety and you have to treat both those conditions. At this point the treatment for motility abnormalitiesare limited. Our treatment plan for each individual

is different depending on what they feel willimprove their quality of life. There's actually a lot of evidence that nontraditional therapies are effective. So we work a lot with the integrative medicine groups. We would recommend acupuncture, mindfulness therapy, and I spend a lot of time speaking to my patients about how to address anxiety, how to address stress, so that they can gain control. We work to provide the care of the whole patient, not just their one organ system. They may be diabetic, so trying to figure out how toeat with diabetes, plus irritable bowel. So, we work together to care for these patients.It's not just a team within GI, we really look at other subspecialties and together,we sit down as a team to come up with the

best treatment plan for that individual.

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